期刊存档
铜绿假单胞菌下呼吸道感染现状与对策
张爱荣张爱荣，河南省 商丘市第一人民医院检验科，476100
摘 要:目的 探讨下呼吸道铜绿假单胞菌感染的现状及耐药性，为其临床治疗和预防提供科学依据。方法 回顾性分析2003年1月至2008年12月629例下呼吸道感染铜绿假单胞菌患者临床特点和药敏结果。结果 下呼吸道标本分离的629株铜绿假单胞菌主要分布于呼吸内科、神经内科、神经外科、ICU。铜绿假单胞菌下呼吸道感染一年四季均有发生，耐药情况严重。下呼吸道感染铜绿假单胞菌患者存在使用抗生素时间长、住院时间长、基础疾病、呼吸机使用等危险因素。结论 铜绿假单胞菌耐药现象十分突出，对铜绿假单胞菌进行严密的监测、建立耐药监控体系、合理应用抗生素、加强住院环境建设对其感染控制和预防至关重要。
关键词:假单胞菌，铜绿； 呼吸道感染； 抗药性，细菌
Present situation and countermeasure of Pseuadomonas aeruginosa in patients with lower respiratory infection
ZHANG Ai-rong.Department of Laboratory Medicine，The First People′s Hospital of Shangqiu，Shangqiu 476100，China
Abstract:Objective To investigate the present situation and drug resistance of Pseuadomonas aeruginosa in patients with lower respiratory infection and provide the scientific basis for preventing and treating the Pseuadomonas aeruginosa infection.Methods The clinical characteristics and drug susceptibility results of Pseuadomonas aeruginosa in patients with lower respiratory infections were analyzed retrospectively in our hospital from January 2003 to December 2008.Results These strains were mainly isolated from Department of Respiratory Disease，Department of Neurology，Department of Neurosurgery and ICU.Lower respiratory infections caused by Pseuadomonas aeruginosa occurred throughout the four seasons of the year.The resistance of Pseuadomonas aeruginosa to antibiotics was sever.It was found that long-term inpatient，frequent use of antimicrobial drugs，basic illness and mechanical ventilation are risk factors of lower respiratory infections caused by Pseuadomonas aeruginosa.Conclusions The drug resistance of Pseuadomonas aeruginosa has become a more serious problem than ever before.It is importment to establish a drug resistance monitoring system，to use antibiotics rationally，to monitor the pathogenic bacteria closely and to strengthen environmental building to prevent and control lower respiratory infections caused by Pseuadomonas aeruginosa.
Key words:Pseudomonas aeruginosa； Respiratory tract infections； Drug resistance，bacterial
文献标引:张爱荣.铜绿假单胞菌下呼吸道感染现状与对策[J/CD].中华临床医师杂志：电子版,2010,4(7):945-948.
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